1449431-63-3Relevant academic research and scientific papers
Exploring the orthosteric binding site of the γ-aminobutyric acid type a receptor using 4-(Piperidin-4-yl)-1-hydroxypyrazoles 3- or 5-imidazolyl substituted: Design, synthesis, and pharmacological evaluation
Krall, Jacob,Jensen, Claus H.,S?rensen, Troels E.,Nielsen, Birgitte,Jensen, Anders A.,Sander, Tommy,Balle, Thomas,Fr?lund, Bente
, p. 6536 - 6540 (2013/09/23)
A series of 4-(piperidin-4-yl)-1-hydroxypyrazole (4-PHP) 3- or 5-imidazolyl substituted analogues have been designed, synthesized, and characterized pharmacologically. All analogues showed binding affinities in the low micro- to low nanomolar range at nat
