1449431-96-2Relevant academic research and scientific papers
Highly enantioselective direct vinylogous Michael addition of γ-substituted deconjugated butenolides to maleimides catalyzed by chiral squaramides
Guo, Yun-Long,Jia, Li-Na,Peng, Lin,Qi, Liang-Wen,Zhou, Jing,Tian, Fang,Xu, Xiao-Ying,Wang, Li-Xin
, p. 16973 - 16976 (2013)
Highly enantioselective direct vinylogous Michael reactions of γ-aryl-substituted deconjugated butenolides with maleimides, catalyzed by only 1 mol% bifunctional squaramides derived from cinchona alkaloids, were achieved with excellent yields (up to 96%) and enantioselectivities (up to 97% ee). This protocol features a very low catalyst loading, mild reaction conditions and provides a potential and effective method for the construction of optically active chiral butenolides with adjacent quaternary and tertiary stereocenters.
Catalytic asymmetric direct vinylogous Michael addition of γ-aryl-substituted deconjugated butenolides to nitroolefins and N-phenylmaleimide
Kumar, Vikas,Ray, Bidisha,Rathi, Preeti,Mukherjee, Santanu
, p. 1641 - 1646 (2013/07/19)
Direct asymmetric vinylogous Michael reactions of γ-aryl-substituted deconjugated butenolides with nitroolefins and N-phenylmaleimide are described using bifunctional thiourea derivatives as the catalyst. The resulting butenolide derivatives containing ad
