144949-47-3

Upstream product

• 6939-93-1 4-bromo-isophthalic acid 

Downstream Products

• 144949-48-4 dimethyl 4-bromo-5-nitroisophthalate 
• 612058-82-9 dimethyl 4-(4-tert-butyl-2-nitrophenoxy)-5-nitroisophthalate 
• 866431-77-8 isopropyl 3-amino-2-(4-tert-butyl-2-nitrophenoxy)-5-[(diisopropylamino)carbonyl]benzoate 
• 866431-76-7 isopropyl 2-(4-tert-butyl-2-nitrophenoxy)-5-[(diisopropylamino)carbonyl]-3-nitrobenzoate 
• 866431-75-6 isopropyl 2-bromo-5-[(diisopropylamino)carbonyl]-3-nitrobenzoate 

Relevant academic research and scientific papers

Xanthone receptors as oxyanion-hole mimics in artificial enzymes

Different xanthone-based receptors (2-10) for lactones and lactams have been prepared, and the feasibility of these compounds to mimic the known enzymatic 'oxyanion-hole' structure is discussed. The self-association of the receptors was found to pose a serious drawback for complex formation. X-Ray crystal structures of receptor dimers allowed us to understand the reasons for their self-association and to improve the design of the catalysts. The catalytic activity of the receptors has been tested towards the nucleophilic addition of pyrrolidine to unsaturated lactones. Since the resulting complexes were very weak in organic solvents, new receptors were developed for lactams, which showed better stabilities, and their catalytic activities were studied.

Poly-iodinated compounds, process for their preparation, contrast medium containing them

The invention relates to novel poly-iodinated compounds of general formula: STR1 in which R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10, identical or different, are selected from an iodine atom, a group of formula STR2 provided that at least two of the R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 groups represent an iodine atom, utilizable in contrast media for radiography. The invention also relates to a process for the preparation of these compounds as well as a contrast medium containing them.