1449490-53-2Relevant academic research and scientific papers
Total synthesis of the cytotoxic anhydrophytosphingosine pachastrissamine (Jaspine B)
Dhand, Vijay,Chang, Stanley,Britton, Robert
, p. 8208 - 8213 (2013)
A short, 8-step synthesis of the marine natural product pachastrissamine has been developed that relies on a diastereoselective aldol reaction between a suitably protected hydantoin and an optically enriched α-chloroaldehyde. This synthetic route provides new opportunities for exploring structure activity relationships within this family of natural products.
