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1449579-77-4

4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1449579-77-4 Structure

  • Basic information

    1. Product Name: 4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid
    2. Synonyms: 4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid
    3. CAS NO:1449579-77-4
    4. Molecular Formula:
    5. Molecular Weight: 291.306
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1449579-77-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid(1449579-77-4)
    11. EPA Substance Registry System: 4-benzyl-4H-furo[3,2-b]indole-2-carboxylic acid(1449579-77-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1449579-77-4(Hazardous Substances Data)

1449579-77-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1449579-77-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,9,5,7 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1449579-77:
(9*1)+(8*4)+(7*4)+(6*9)+(5*5)+(4*7)+(3*9)+(2*7)+(1*7)=224
224 % 10 = 4
So 1449579-77-4 is a valid CAS Registry Number.

1449579-77-4Downstream Products

1449579-77-4Relevant articles and documents

Synthesis and anticancer activity of 2,4-disubstituted furo[3,2-b] indole derivatives

Zhuang, Shi-Hong,Lin, Yi-Chien,Chou, Li-Chen,Hsu, Mei-Hua,Lin, Hui-Yi,Huang, Chi-Hung,Lien, Jin-Cherng,Kuo, Sheng-Chu,Huang, Li-Jiau

, p. 466 - 479 (2013/10/01)

We synthesized and evaluated a series of 2,4-disubstituted furo[3,2-b]indole derivatives for anticancer activity and established the structure - activity relationships (SARs) of these compounds. Among all tested compounds, we found (5-((2-(hydroxymethyl)-4H-furo[3,2-b]indol-4-yl)methyl) furan-2-yl) methanol (10a) to be the most promising agent. In screening against NCI-60 human tumor cell lines, 10a exhibited highly selective anticancer activity and significant inhibitory activity against A498 renal cancer cells. Our COMPARE analysis results suggest that the 10a fingerprint is similar to that of NSC-754549, which is an isostere of YC-1. We further con firmed the significant antitumor activity of compound 10a with tests in the A498 xenograft nude mice model. Therefore, compound 10a should be further developed as a new drug candidate for treating renal cancer.

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