144966-96-1 Usage
Originator
WY-50324 ,Centre de Recherche
Pierre Fabre
Manufacturing Process
To a stirred solution of [4-(2-pyrimidinyl)piperazino]ethylamine (2.0 g, 0.01
mol) in 50 ml of methylene chloride, adamantane-1-carboxylic acid chloride
(3.6 g, 0.018 mol) and triethylamine (2.9 g, 0.015 mol) were added. Stirring
was continued at room temperature overnight. The methylene chloride
solution was washed with water, dried over anhydrous sodium sulfate and
evaporated under reduced pressure. The remaining residue was subjected to
preparative HPLC. The residue was dissolved in ethyl acetate (10 ml) and
subjected to flash chromatography using a 9 inch column of silica gel and
ethyl acetate as the eluent. The N-[2-[4-(2-pyrimidinyl)-1-
piperazinyl]ethyl]tricyclo[3.3.1.1(3,7)]
decane-1-carboxamide was separated.In practice it is usually used as hydrochloride.
Therapeutic Function
Anxiolyticá Antidepressant
Check Digit Verification of cas no
The CAS Registry Mumber 144966-96-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,9,6 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 144966-96:
(8*1)+(7*4)+(6*4)+(5*9)+(4*6)+(3*6)+(2*9)+(1*6)=171
171 % 10 = 1
So 144966-96-1 is a valid CAS Registry Number.
