1449688-88-3Relevant academic research and scientific papers
Synthesis of chiral amino acid anilides by ligand-free copper-catalyzed selective N-arylation of amino acid amides
Dong, Junyu,Wang, Yan,Xiang, Qinjie,Lv, Xirui,Weng, Wen,Zeng, Qingle
, p. 692 - 696 (2013)
An atom-economic, practical and cost-effective protocol for synthesis of chiral amino acid anilides via ligand-free copper-catalyzed selective C-N cross coupling of chiral amino acid amides and aryl halides, hetereoaryl halides and a vinyl bromide has been developed. No racemization occurred during the C-N coupling. A plausible mechanism is proposed. Copyright
