1449736-73-5

Basic information

• Product Name: N-(4,4-difluorocyclohexyl)-8-nitroquinazolin-4-amine
• Synonyms: N-(4,4-difluorocyclohexyl)-8-nitroquinazolin-4-amine
• CAS NO: 1449736-73-5
• Molecular Weight: 308.288
• Mol File: 1449736-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4,4-difluorocyclohexyl)-8-nitroquinazolin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4,4-difluorocyclohexyl)-8-nitroquinazolin-4-amine(1449736-73-5)
• EPA Substance Registry System: N-(4,4-difluorocyclohexyl)-8-nitroquinazolin-4-amine(1449736-73-5)

Safety Data

• Hazardous Substances Data: 1449736-73-5(Hazardous Substances Data)

Upstream product

• 606-18-8 3-nitroanthranilic acid 
• 53638-54-3 8-nitroquinazoline-4(3H)-one 
• 458566-84-2 4,4-difluorocyclohexan-1-amine 
• 19815-18-0 4-chloro-8-nitroquinazoline 

Downstream Products

• 1449736-72-4 N⁴-(4,4-difluorocyclohexyl)quinazoline-4,8-diamine 

Relevant articles and documents

BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.