14499-33-3Relevant articles and documents
Synthesis of C3-alkenylated 2,3,4-trisubstituted pyrrole derivatives through cyclization of methylene isocyanides and ene-yne-ketones
Li, Shasha,Zeng, Gongruixue,Xing, Xiaoqi,Yang, Zhiheng,Ma, Feiyun,Li, Boxia,Cheng, Weiyan,Zhang, Jiankang,He, Ruoyu
, p. 1834 - 1837 (2021)
A mild, transition-metal-free and facile C3-alkenylated 2,3,4-trisubstituted pyrrole cyclization of methylene isocyanides with ene-yne-ketones in moderate to good yields was explored. The E-alkenylated products were isolated in moderate to exclusive selec
Phosphine-Mediated Dimerization of Conjugated Ene-Yne Ketones: Stereoselective Construction of Dihydrobenzofurans
Zhu, Cheng-Zhi,Sun, Yao-Liang,Wei, Yin,Shi, Min
, p. 1263 - 1270 (2017/04/18)
A new strategy for the phosphine-mediated dimerization of conjugated ene-yne ketones to produce functionalized dihydrobenzofurans has been developed, affording diversified 4,5-dihydrobenzofurans in moderate to excellent yields with high diastereoselectivities under mild conditions. This new synthetic method can tolerate a variety of functional groups and can be performed on a gram scale and in an asymmetric variant using the chiral phosphine Xyl-BINAP to give the desired products with up to 94% ee. (Figure presented.).
Csp3-P versus Csp2-P bond formation: Catalyst-controlled highly regioselective tandem reaction of Ene-Yne-ketones with H-phosphonates
Yu, Yue,Yi, Songjian,Zhu, Chuanle,Hu, Weigao,Gao, Bingjie,Chen, Yang,Wu, Wanqing,Jiang, Huanfeng
supporting information, p. 400 - 403 (2016/02/18)
Under copper-catalyzed or base-promoted conditions, a wide range of ene-yne-ketones react with H-phosphonates to afford various phosphorylated furans in good yields. A copper carbene generation or a Michael addition is proposed as the key step in the sele
