145032-05-9

Upstream product

• 62054-49-3 ethyl (E)-3-formyl-2-butenoate 
• 163395-64-0 (E)-tert-butyldimethylsilyl-(4,4-ethylenedioxy-3-methylbut-2-en-1-yl) ether 
• 65527-87-9 ethyl (E)-4,4-ethylenedioxy-3-methylbut-2-enoate 
• 144950-82-3 (E)-4-(t-butyl-dimethyl-silanyloxy)-2-methyl-but-2-enal 
• 65527-78-8 (E)-4,4-ethylenedioxy-3-methylbut-2-en-1-ol 
• 144950-81-2 <(E,E)-4-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)buta-1,3-dien-1-yl>boronic acid 
• 144950-84-5 tert-butyldimethylsilyl-<(2E,4E)-5-iodo-3-methylpenta-2,4-dien-1-yl> ether 

Downstream Products

• 24336-19-4 all-trans-9-desmethyltretinal 
• 4834-01-9 9-demethylretinol 

Relevant academic research and scientific papers

Stereospecific Synthesis of 9-Demethylretinoids via Palladium-Catalyzed Vinylboronic Acid-Vinyl Iodide Cross Coupling

A stereospecific synthesis of 9-demethylretinoids with either trans or 11-cis geometries, based on the thallium-accelerated palladium-catalyzed cross-coupling reactions of (E)-1-alkenylboronic acid and (E) or (Z)-alkenyl iodides, is described.