145046-17-9

Upstream product

• 157646-08-7 t-butyl 5--3-(2-methoxycarbonylethyl)-4-methoxycarbonylmethylpyrrole-2-carboxylate 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 145046-21-5 8-(2-Methoxycarbonylethyl)-7-methoxycarbonylmethyl-3,3-dimethyl-1-methylthio-5-(p-tolylsulfonylaminomethyl)-2,3-dihydropyrrin-9-carbaldehyde 
• 145046-18-0 tert-Butyl (E)-8-(2-methoxycarbonylethyl)-7-methoxycarbonylmethyl-3,3-dimethyl-1-thioxo-5-(p-tolylsulfonylaminomethyl)-1,2,3,10-tetrahydropyrrin-9-carboxylate 
• 145046-27-1 tert-Butyl (Z)-8-(2-methoxycarbonylethyl)-7-methoxycarbonylmethyl-3,3-dimethyl-1-thioxo-5-(p-tolylsulfonylaminomethyl)-1,2,3,10-tetrahydropyrrin-9-carboxylate 

Relevant academic research and scientific papers

Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 11. Modification of the East and West Building Blocks and Study of Different Assembly Methods for Synthesis of Isobacteriochlorins

The eastern and western building blocks required for the photochemical route to isobacteriochlorins have been synthesized by a C-C bond-forming step which leaves a cyano group on the bridge carbon, e.g. 5.Two methods have been developed to remove this cya