145064-01-3

Upstream product

• 768-33-2 phenyldimethylsilyl chloride 
• 145064-07-9 (1Z,3R,4S,5S)-5-dibenzylamino-3-dimethylphenylsilyl-4-hydroxy-7-methyl-1-octenyl N,N-diisopropylcarbamate 
• 145064-04-6 (2S,3R,5RS)-2-<(S)-1-dibenzylamino-3-methylbutyl>-3-dimethylphenylsilyl-5-methoxytetrahydrofuran 
• 145064-09-1 (3R,4S,5S)-5-dibenzylamino-3-dimethylphenylsilyl-7-methyl-4-octanolide 
• 145064-05-7 (Z)-3-dimethylphenylsilyl-2-propenyl N,N-diisopropylcarbamate 
• 136320-55-3 3-(dimethylphenylsilyl)-2-propynyl N,N-diisopropylcarbamate 
• 111060-65-2 (S)-2-(dibenzylamino)-4-methylpentanal 
• 145064-13-7 (2S,3R,4S,5S)-5-dibenzylamino-3-dimethylphenylsilyl-2-(1-hydroxy-1-methylethyl)-7-methyl-4-octanolide 

Downstream Products

• 145064-15-9 (2S,3R,4S,5S)-5-amino-3-dimethylphenylsilyl-2-isopropyl-7-methyl-4-octanolide 
• 145064-00-2 (2S,3R,4S,5S)-5-dibenzylamino-3-dimethylphenylsilyl-2-isopropyl-7-methyl-4-octanolide 

Relevant academic research and scientific papers

Synthesis of dihydroxyethylene isosteres of dipeptides. 1. Enantiomerically and diastereomerically pure 2-alkyl-5-amino-3-dimethylphenylsilyl-4-octanolides from (S)-N,N-dibenzylleucinal

5-Dibenzylamino-3-dimethylphenylsilyl-4-octanolides are prepared via homoenolate addition of (S)-N,N-dibenzylleucinal [(S)-2-dibenzylamino-4-methylpentanal] and metalated 3-dimethylphenylsilyl-2-propenyl N,N-diisopropylcarbamate, followed by oxidative lac