145064-02-4Relevant academic research and scientific papers
Synthesis of dihydroxyethylene isosteres of dipeptides; 2. Isosteres of Leu-Ala and Leu-Val from suitably substituted 3-dimethylphenylsilyl-4-octanolides
Rehders,Hoppe
, p. 865 - 870 (1992)
Homochiral 2-alkyl-5-amino-3-hydroxy-5-octanolides 4a,b, 5b, 6b and 9a, representing protected Ψ [CHOHCHOH] dipeptides, were prepared by stereospecific oxydesilylation of the appropriate 3-dimethylphenylsilyl derivatives, 1a-c and 7a. Alternatively, antis
