1450812-08-4Relevant academic research and scientific papers
Gold(I)-catalyzed enantioselective carboalkoxylation of alkynes
Zi, Weiwei,Toste, F. Dean
, p. 12600 - 12603 (2013)
A highly enantioselective carboalkoxylation of alkynes catalyzed by cationic (DTBM-MeO-Biphep)gold(I) complexes is reported. Various optically active β-alkoxyindanone derivatives were obtained in good yields with high enantioselectivities. Furthermore, this methodology was extended to the enantioselective synthesis of 3-methoxycyclopentenones. The reaction is proposed to proceed through an enantioselective cyclization of intermediates containing vinylgold(I) and prochiral oxocarbenium moieties.
