1450828-22-4Relevant articles and documents
Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulence
Zender, Michael,Klein, Tobias,Henn, Claudia,Kirsch, Benjamin,Maurer, Christine K.,Kail, Dagmar,Ritter, Christiane,Dolezal, Olan,Steinbach, Anke,Hartmann, Rolf W.
, p. 6761 - 6774 (2013/10/01)
The human pathogen Pseudomonas aeruginosa employs alkyl quinolones for cell-to-cell communication. The Pseudomonas quinolone signal (PQS) regulates various virulence factors via interaction with the transcriptional regulator PqsR. Therefore, we consider t