145083-31-4Relevant academic research and scientific papers
Single-flask polyfunctionalization of the imidazole ring; a streamlined route to the antitumor agent carmethizole
Lipshutz, Bruce H.,Hagen, William
, p. 5865 - 5868 (2007/10/02)
Three sequential treatments of an N-protected tribromoimidazole with n-BuLi/electrophile in a 1-pot process leads to N-protected 2,4,5-trisubstituted imidazoles. The method can be applied to the preparation of the immediate of carmethizole.
