1450841-25-4 Usage
General Description
2,6-Bis[(2S,3S)-4-Methyl-5,5-diphenyloxazolidin-2-yl]pyridine is a chemical compound used as a chiral ligand in asymmetric catalysis. It is a versatile and efficient ligand in various organic transformations such as asymmetric hydrogenation, allylic substitution, and cyclopropanation reactions. The compound features two oxazolidine rings, each with a methyl and phenyl group attached to the nitrogen atom. These oxazolidine rings confer chirality to the compound, making it a valuable tool for controlling the stereochemistry of chemical reactions. 2,6-Bis[(2S,3S)-4-Methyl-5,5-diphenyloxazolidin-2-yl]pyridine plays a crucial role in the development of new synthetic methodologies and the production of enantiomerically pure compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1450841-25-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,0,8,4 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1450841-25:
(9*1)+(8*4)+(7*5)+(6*0)+(5*8)+(4*4)+(3*1)+(2*2)+(1*5)=144
144 % 10 = 4
So 1450841-25-4 is a valid CAS Registry Number.
1450841-25-4Relevant articles and documents
Chiral Bis(oxazolidine)pyridine-copper-catalyzed enantioselective friedel-crafts alkylation of indoles with nitroalkenes
Sato, Toru,Arai, Takayoshi
, p. 349 - 354 (2014/03/21)
Catalytic asymmetric Friedel-Crafts reaction of indoles with nitroalkenes was catalyzed by the stereochemically tunable bis(oxazolidine)pyridine (PyBodine)-Cu(OTf)2 complex. Using the PyBodine(Val)-Cu(OTf) 2 catalyst gave the Friedel-Crafts ?adducts with highly enantioselective manner. For the 1,4-bis[(E)-2-nitrovinyl]benzene, the reaction proceeded in a meso-trick manner to give the chiral double Friedel-Crafts adduct with 97% enantiomeric excess. Georg Thieme Verlag Stuttgart New York.
