1450841-27-6 Usage
Chemical class
Pyridine derivatives
Stereochemistry
Highly selective ligand for the α4β2 nicotinic acetylcholine receptor
Potential pharmaceutical applications
Treatment of neurological disorders such as Alzheimer's disease and Parkinson's disease
Unique structural features
Interesting candidate for drug design and development
Need for further research
To fully understand its pharmacological properties and potential therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 1450841-27-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,0,8,4 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1450841-27:
(9*1)+(8*4)+(7*5)+(6*0)+(5*8)+(4*4)+(3*1)+(2*2)+(1*7)=146
146 % 10 = 6
So 1450841-27-6 is a valid CAS Registry Number.
1450841-27-6Relevant articles and documents
Development of a tailor-made bis(oxazolidine)pyridine-metal catalyst for the [3+2] cycloaddition of azomethine imines with propiolates
Arai, Takayoshi,Ogino, Yuta,Sato, Toru
supporting information, p. 7776 - 7778 (2013/09/02)
A series of bis(oxazolidine)pyridine ligands (the PyBodines) were newly designed and synthesized for the development of a highly efficient, tailor-made catalyst for the [3+2] cycloaddition of azomethine imines with propiolates. The PyBodine(l-Ala)-Cu(OAc)2 catalyst was selected on the basis of solid-phase catalysis/CD-HTS and exhibited high efficiency, producing the (R)-adducts with excellent enantioselectivity.
