1450852-60-4

Upstream product

• 1450852-59-1 N-(2-pyridylmethyl),N’(-4-thiomethoxy-2-pyridylmethyl)amine 
• 195621-22-8 2-(N,N-bis((pyridin-2-yl)methyl)aminomethyl)-6-chloromethyl-4-methylphenol 
• 159150-90-0 2-(N,N-bis(2-pyridinylmethyl)aminomethyl)-6-(hydroxymethyl)-4-methylphenol 
• 1450852-58-0 N-(2-pyridylmethyl), N’(-5-thiomethoxy-2-pyridylmethyl)amine 
• 1093967-05-5 2-hydroxymethyl-5-thiomethoxypyridine 
• 206990-46-7 2-hydroxymethyl-4-thiomethoxypyridine 
• 326592-79-4 2-Chloromethyl-4-methylsulfanyl-pyridine 

Relevant academic research and scientific papers

Thiomethyl substituted dicopper complexes: Attempts to reproduce the asymmetry of the active site from type 3 copper enzymes

Two new dinucleating phenol-based ligands (m-HLSMe and p-HL SMe) bearing pyridine-containing pendant arms with a SMe group on one pyridine (meta or para position relative to the pyridine nitrogen atom) have been synthesized. After coordination by two copper(II) ions, the corresponding μ-phenoxido, μ-hydroxido dicopper(II) complexes were isolated and characterized by UV/Vis, EPR spectroscopy, single-crystal X-ray analysis (for the complex with the SMe substituent at the meta position) and electrochemistry. The presented compounds mimic the active site of type 3 copper enzymes and in particular the distinct environments of the copper ions.Both complexes are active as catalysts for the oxidation of 3, 5-di-tert-butylcatechol to the respective quinone. The catalytic properties of the complexes depend on substrate binding, as reflected by the KM values determined for the complexes in presence of 3, 5-dtbc and are not correlated directly with the redox properties of the dicopper center. Copyright