1450912-84-1

Basic information

• Product Name: C₃₃H₄₀Cl₂F₂N₈O₃
• Synonyms: C₃₃H₄₀Cl₂F₂N₈O₃
• CAS NO: 1450912-84-1
• Molecular Weight: 705.635
• Mol File: 1450912-84-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₃H₄₀Cl₂F₂N₈O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₃H₄₀Cl₂F₂N₈O₃(1450912-84-1)
• EPA Substance Registry System: C₃₃H₄₀Cl₂F₂N₈O₃(1450912-84-1)

Safety Data

• Hazardous Substances Data: 1450912-84-1(Hazardous Substances Data)

Upstream product

• 380843-75-4 bosutinib 
• 1450912-65-8 2-((7-chloro-1,1-difluoroheptyl)sulfonyl)pyridine 
• 1450912-66-9 2-[(7-azido-1,1-difluoroheptyl)sulfonyl]pyridine 

Relevant articles and documents

Bioconjugation by native chemical tagging of C-H bonds

A general C-H functionalization method for the tagging of natural products and pharmaceuticals is described. An azide-containing sulfinate reagent allows the appendage of azidoalkyl chains onto heteroaromatics, the product of which can then be attached to a monoclonal antibody by a click reaction. This strategy expands the breadth of bioactive small molecules that can be linked to macromolecules in a manner that is beyond the scope of existing methods in bioconjugation to permit tagging of the seemingly untaggable .