1450922-44-7

Basic information

• Product Name: 4-(2-cyano-4-isopropylphenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide
• Synonyms: 4-(2-cyano-4-isopropylphenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide
• CAS NO: 1450922-44-7
• Molecular Weight: 440.547
• Mol File: 1450922-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-cyano-4-isopropylphenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-cyano-4-isopropylphenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide(1450922-44-7)
• EPA Substance Registry System: 4-(2-cyano-4-isopropylphenyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide(1450922-44-7)

Safety Data

• Hazardous Substances Data: 1450922-44-7(Hazardous Substances Data)

Upstream product

• 1000578-18-6 2-bromo-1-iodo-4-isopropylbenzene 
• 1450923-74-6 4-(2-bromo-4-isopropylphenyl)-N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide 
• 1450923-24-6 N-(4-methoxybenzyl)-N-(thiazol-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonamide 

Relevant articles and documents

DIHYDROBENZOXAZINE AND TETRAHYDROQUINOXALINE SODIUM CHANNEL INHIBITORS

The present invention provides compounds of Formula I, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.