1450930-07-0

Basic information

• Product Name: propyl 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carboxylate
• CAS NO: 1450930-07-0
• Molecular Weight: 385.419
• Mol File: 1450930-07-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: propyl 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: propyl 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carboxylate(1450930-07-0)
• EPA Substance Registry System: propyl 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carboxylate(1450930-07-0)

Safety Data

• Hazardous Substances Data: 1450930-07-0(Hazardous Substances Data)

Upstream product

• 1450930-02-5 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carboxamide 
• 1450930-00-3 4-oxo-8-phenyl-2-(pyridin-4-yl)-4H-chromene-6-carbonitrile 
• 1450929-98-2 8-bromo-4-oxo-2-(pyridin-4-yl)-4H-chromene-6-carbonitrile 
• 35794-84-4 2-hydroxy-5-cyanoacetophenone 
• 13031-41-9 4-cyanophenyl acetate 
• 767-00-0 4-cyanophenol 

Relevant articles and documents

Potent Inhibitors of Phosphatidylinositol3 (PI3) Kinase that have Antiproliferative Activity Only When Delivered as Prodrug Forms

Prodrugs for PI3K: A series of substituted analogues of the phosphatidylinositol3 kinase (PI3K) inhibitor LY294002 were prepared and found to potently inhibit the isolated enzyme but not MCF7 cell proliferation. Two tetrazolyl-substituted analogues were further derivatized as prodrugs resulting in restoration of cell-based activity. These data provide a conceptual model for development of tumor-targeting prodrug forms of cell-impermeable PI3K inhibitors. Copyright