145096-24-8Relevant articles and documents
Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: Synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives
Hibi,Okamoto,Tagami,Numata,Kobayashi,Shinoda,Kawahara,Murakami,Oketani,Inoue,Shibata,Yamatsu
, p. 3062 - 3070 (2007/10/02)
As part of our search for novel antiinflammatory drug candidates, we have designed and synthesized a series of 3-pyridylmethyl-substituted 2-amino-6- hydroxybenzothiazoles. Introduction of a 3-pyridylmethyl group into the 2- amino group (type-A) or the be