1450975-46-8

Upstream product

• 1450975-45-7 (-)-(6aR,8S,9R,9aR)-9-fluoro-2,2,4,4-tetraisopropyltetrahydro-6H-spiro[cyclopenta[f][1,3,5,2,4]trioxadisilocine-7,1'-cyclopropan]-8-ol 
• 2775-87-3 3-N-benzoyluracil 
• 1450975-44-6 (-)-(6aR,8S,9R,9aR)-8-(benzyloxy)-9-fluoro-2,2,4,4-tetraisopropyltetrahydro-6H-spiro[cyclopenta[f][1,3,5,2,4]trioxadisilocine-7,1'-cyclopropane] 
• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 
• 1450975-43-5 (-)-(6aR,8S,9S,9aR)-8-(benzyloxy)-2,2,4,4-tetraisopropyltetrahydro-6H-spiro[cyclopenta[f][1,3,5,2,4]trioxadisilocine-7,1'-cyclopropan]-9-ol 
• 1450975-42-4 (-)-(4S,5R,6R,7R)-4-(benzyloxy)-7-(hydroxymethyl)spiro[2.4]heptane-5,6-diol 
• 1450975-41-3 (-)-(((3aR,4S,6R,6aR)-4-(benzyloxy)-2,2-dimethyltetrahydrospiro[cyclopenta[d][1,3] dioxole-5,1'-cyclopropan]-6-yl)methoxy)(tert-butyl)dimethylsilane 
• 1450975-35-5 (-)-(3aR,4R,6S,6aS)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyltetrahydrospiro[cyclopenta[d][1,3]dioxole-5,1’-cyclopropan]-6-ol 
• 1450975-34-4 (3aR,6R,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-5-methylenetetrahydro-4H-cyclopenta[d][1,3]dioxol-4-one 
• 1450975-33-3 (-)-(3aS,4S,6R,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-5-methylene-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol 
• 1450975-32-2 (-)-(3aS,4R,6R,6aR)-6-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-5-methylenetetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ol 
• 1450975-31-1 (1)-tert-butyl(((1aR,1bR,4aR,5S,5aR)-3,3-dimethyltetrahydro-1aH-oxireno[2’,3’:3,4]-cyclopenta[1,2-d][1,3]dioxol-5-yl)methoxy)dimethylsilane 
• 503303-03-5 (3S,4R,5R)-3,4-O-isopropylidene-5-hydroxymethylcyclopentene-3,4-diol 
• 1450975-30-0 ⁽¹⁾-tert-butyl(((3aR,4R,6aS)-2,2-dimethyl-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)methoxy)dimethylsilane 

Relevant academic research and scientific papers

SPIRO [2.4]HEPTANES FOR TREATMENT OF FLAVIVIRIDAE INFECTIONS

Compounds, methods, and compositions for the treatment of infections in or exposure to humans and other host animals of Flaviviridae viruses, including HCV, that includes the administration of an effective amount of a spiro[2.4]heptane as described herein