1450992-06-9Relevant academic research and scientific papers
A facile synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydrobenzo[b]imidazo[1,2,3-ij][1,8]naphthyridines through NHC-catalyzed cascade annulations
Yao, Changsheng,Jiao, Weihui,Xiao, Zhaoxin,Xie, Yuanwei,Li, Tuanjie,Wang, Xiangshan,Liu, Rui,Yu, Chenxia
, p. 10801 - 10805 (2013/09/02)
A new efficient approach for the synthesis of tetrahydroimidazo[1,2-a] pyridines and tetrahydrobenzo[b]imidazo[1,2,3-ij][1,8]naphthyridines with biological significance was successfully developed through a NHC-catalyzed cascade C-C bond and C-N bond formation process. This new alternative approach for the assembly of these multi-functionalized nitrogen bridgehead-fused heterocycles features mild conditions, moderate to high yields and operational simplicity. The Royal Society of Chemistry 2013.
