145100-08-9Relevant academic research and scientific papers
Dihydropyrromethenones by Pd(0)-Mediated Coupling of Iodopyrroles and Acetylenic Amides. Synthesis of the A,B-Ring Segment of Phytochrome
Jacobi, Peter A.,Guo, Jiasheng,Rajeswari,Zheng, Wanjun
, p. 2907 - 2916 (2007/10/03)
Dihydropyrromethenone derivative 32b, which constitutes the A,B-ring segment of phytochrome (6), has been prepared in enantiomerically pure form beginning with acetylenic amide 47b and iodopyrrole 27. The key steps involved the TBAF-catalyzed 5-exo-dig cyclization of the acetylenic pyrrole 48b, followed by thia-Mitsunobu inversion of the resulting alcohol derivative 31b.
Tetrapyrroles. IV. A highly efficient synthesis of homochiral dihydropyrromethenones via Pd○ mediated coupling of iodopyrroles and acetylenic amides
Jacobi, Peter A.,Rajeswari
, p. 6235 - 6238 (2007/10/02)
Homochiral dihydropyrromethenones of type 20 have been synthesized in a highly efficient manner by Pd○ mediated coupling of iodopyrrole 14 with acetylenic amides 18, followed by F- catalyzed 5-exo-dig cyclization. In analogous fashion, phytochr
