1451051-43-6Relevant articles and documents
Direct asymmetric Michael addition of phthalide derivatives to chalcones
Luo, Jie,Jiang, Chunhui,Wang, Haifei,Xu, Li-Wen,Lu, Yixin
supporting information, p. 5261 - 5265 (2013/09/02)
The Michael addition of phthalides to chalcones employing a quinidine-derived thiourea catalyst Q-1 has been developed. The reported method led to the synthesis of 3,3-disubstituted phthalide derivatives in excellent yields, with excellent diastereo- and enantioselectivities.