1451055-75-6Relevant academic research and scientific papers
Enantioselective synthesis of anti-β-amido-α-hydroxy esters via asymmetric transfer hydrogenation coupled with dynamic kinetic resolution
Villacrez, Marvin,Somfai, Peter
, p. 5266 - 5268 (2013)
The asymmetric transfer hydrogenation of β-amido-α-keto esters providing the corresponding anti-β-amido-α-hydroxy esters via dynamic kinetic resolution is reported. The use of a commercially available, or simply prepared, chiral ruthenium catalyst results in good yields as well as high diastereoselectivities and enantioselectivities.
