1451069-25-2

Upstream product

• 285984-25-0 3-tert-butyl-1-p-tolyl-1H-pyrazol-5-amine 
• 591-27-5 m-Hydroxyaniline 
• 1229607-47-9 C₁₈H₂₁N₅O 
• 476011-71-9 4-(2-chloro-pyrimidin-4-yloxy)-naphthalen-1-ylamine 

Relevant academic research and scientific papers

L-PYRAZOLYL-3- (4- ( (2 -ANILINOPYRIMIDIN- 4 - YL) OXY) NAPTHTHALEN- 1 - YL) UREAS AS P3I MAP KINASE INHIBITORS

There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD.

1-Pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl)oxy)napththalen-1-yl)ureas as p38 MAP kinase inhibitors

There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, in