1451154-29-2Relevant academic research and scientific papers
One-pot anti-markovnikov hydroamination of unactivated alkenes by hydrozirconation and amination
Strom, Alexandra E.,Hartwig, John F.
, p. 8909 - 8914 (2013/09/24)
A one-pot anti-Markovnikov hydroamination of alkenes is reported. The synthesis of primary and secondary amines from unactivated olefins was accomplished in the presence of a variety of functional groups. Hydrozirconation, followed by amination with nitrogen electrophiles, provides exclusive anti-Markovnikov selectivity. Most products are isolated in high yields without the use of column chromatography.
