1451265-40-9Relevant academic research and scientific papers
Halonium ion mediated synthesis of 2-halomethylene-3-oxoketoxime derivatives from isoxazoline N -oxides
Raihan, Mustafa J.,Rajawinslin,Kavala, Veerababurao,Kuo, Chun-Wei,Kuo, Ting-Shen,He, Chiu-Hui,Huang, Hsiu-Ni,Yao, Ching-Fa
, p. 8872 - 8879 (2013)
A protocol for the N-bromosuccinimide (NBS)- and trichloroisocyanuric acid (TCCA)-mediated synthesis of novel 2-halomethylene-3-oxoketoximes via one-pot halogenation/oxidation of isoxazoline N-oxide derivatives is described here. The keto functionality of 3-ketoximes was selectively reduced by lithiumaluminum hydride to synthesize an unprecedented type of Baylis-Hillman oxime, which underwent N-O coupling to produce new isoxazoline N-oxide derivative.
