1451265-51-2Relevant academic research and scientific papers
Successive formation of two amide linkages between two benzene rings
Yokoyama, Akihiro,Karasawa, Makoto,Taniguchi, Masahisa,Yokozawa, Tsutomu
, p. 641 - 642 (2013/07/27)
To successively construct two amide bonds between two benzene rings, the reaction of methyl N-alkylanthranilate and N-alkylisatoic anhydride in the presence of a base was studied. When the reaction was carried out with lithium hexamethyldisilazide and N,N,N,N-tetramethylethylenediamine in THF at 70 °C under reduced pressure, a cyclic diamide was obtained in high yield.
