145131-22-2 Usage
Chemical structure
A small molecule drug with a complex chemical structure, consisting of a urea group connected to a phenyl ring and a cyclopentyl ring.
Target receptor
A potent and selective antagonist for the neurokinin-2 receptor (NK2) in vitro and in vivo.
Mechanism of action
Inhibits the binding of the endogenous ligand substance P to the NK2 receptor, modulating the release of neurotransmitters.
Therapeutic potential
Shows promise in the treatment of various psychiatric and gastrointestinal disorders, particularly in the management of depression and irritable bowel syndrome.
Clinical applications
Further research is ongoing to explore the full therapeutic potential and safety profile of TAK-220.
Chemical class
A urea-based small molecule.
Molecular weight
Approximately 453.60 g/mol
Solubility
Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
Stability
Stable under standard laboratory conditions.
Route of administration
The specific route of administration for TAK-220 has not been mentioned in the provided material, but it is likely to be oral or intravenous, as these are common routes for small molecule drugs.
Pharmacokinetics
The pharmacokinetic properties of TAK-220, such as absorption, distribution, metabolism, and excretion, are not provided in the material.
Drug interactions
Information on potential drug interactions with TAK-220 is not provided in the material, but this is an important aspect to consider in drug development and clinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 145131-22-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,3 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 145131-22:
(8*1)+(7*4)+(6*5)+(5*1)+(4*3)+(3*1)+(2*2)+(1*2)=92
92 % 10 = 2
So 145131-22-2 is a valid CAS Registry Number.
