1451360-19-2Relevant academic research and scientific papers
KOtBu-mediated stereoselective addition of quinazolines to alkynes under mild conditions
Zhao, Dan,Shen, Qi,Zhou, Yu-Ren,Li, Jian-Xin
, p. 5908 - 5912 (2013/09/12)
A facile alkenylation of quinazolines with unactivated terminal alkynes has been achieved in the presence of KOtBu without the aid of any transition metal catalysts. The reaction is carried out under very mild conditions and shows a high stereoselectivity
