1451391-19-7 Usage
Chemical structure
The compound contains a boron atom bonded to a phenyl ring with a bromine and fluorine atom, and a tetramethyl group attached to a 1,3,2-dioxaborolane ring.
Classification
It is a boronic ester.
Usage
The compound is often used as a reagent in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds.
Stability
2-(4-bromo-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is known for its high stability.
Reactivity
The compound is highly reactive, making it a valuable tool in the field of organic chemistry.
Applications
It is used in the preparation of pharmaceuticals and agrochemicals, as well as in the development of materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1451391-19-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,1,3,9 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1451391-19:
(9*1)+(8*4)+(7*5)+(6*1)+(5*3)+(4*9)+(3*1)+(2*1)+(1*9)=147
147 % 10 = 7
So 1451391-19-7 is a valid CAS Registry Number.
1451391-19-7Relevant articles and documents
Ligand-Enabled, Iridium-Catalyzed ortho-Borylation of Fluoroarenes
Kuleshova, Olena,Asako, Sobi,Ilies, Laurean
, p. 5968 - 5973 (2021/05/31)
A terpyridine derivative and an iridium complex catalyze the C-H borylation of a stoichiometric amount of a fluoroarene with high ortho-selectivity and tolerance of functional groups such as bromide, chloride, ester, ketone, amine, and in situ-borylated hydroxyl. Complex drug molecules such as haloperidol can be selectively borylated ortho to the F atom. The terpyridine ligand undergoes rollover cyclometalation to produce an N,N,C-coordinated iridium complex, which may either selectively borylate the fluoroarene by itself or undergo reductive elimination to produce a borylated ligand.
