145146-17-4

Upstream product

• 138723-23-6 isopropyl (4-methoxyphenyl) sulfoxide 

Downstream Products

• 145146-25-4 (S)-4-(4-Methoxy-phenylsulfanyl)-2-[2-oxo-2-(2-oxo-oxazolidin-3-yl)-ethyl]-pent-4-enoic acid methyl ester 
• 145146-21-0 (1R,2R,3R)-3-(4-Methoxy-phenylsulfanyl)-3-methyl-2-(2-oxo-oxazolidine-3-carbonyl)-cyclobutanecarboxylic acid methyl ester 
• 1220093-83-3 1-[1-(4-methoxyphenylsulfanyl)-1-methylethyl]-3-(1-{[1-(4-methoxyphenylsulfanyl)-1-methylethyl]indol-3-yl}-1-methylethyl)indole 
• 1220093-79-7 1-[1-(4-methoxyphenylsulfanyl)-1-methylethyl]-3-methylindole 

Relevant academic research and scientific papers

Synthesis of 1-(1-arylsulfanylalkyl)indoles and 2,2-bis[1-(1-arylsulfanylalkyl)indol-3-yl]propanes by acid-catalyzed reactions of indoles with aryl vinyl sulfides

We report a facile synthesis of 1-(1-arylsulfanylalkyl)indoles and 2,2-bis[1-(1-arylsulfanylalkyl)indol-3-yl]propanes under mild conditions. Thus, treatment of 3-substituted indoles with aryl vinyl sulfides in dichloromethane at room temperature in the presence of a catalytic amount of (±)-camphor-10-sulfonic acid yields the former indole derivatives in moderate to fair yields. 3-Nonsubstituted indoles can be transformed into the latter indole derivatives in satisfactory yields on treatment with excess aryl vinyl sulfides in the presence of a catalytic amount of the acid under similar conditions.