145162-61-4

Upstream product

• 145162-47-6 1-benzyl-1H-pyrazole-2-oxide 
• 145162-54-5 2-benzyl-3-bromopyrazole 1-oxide 
• 10199-67-4 1-benzylpyrazole 

Downstream Products

• 145162-65-8 2-benzyl-4-bromopyrazole 1-oxide 
• 145162-66-9 2-benzyl-4,5-dibromopyrazole 1-oxide 
• 145162-59-0 2-benzyl-3,4-dibromopyrazole 1-oxide 
• 145162-57-8 2-benzyl-4-bromo-3-chloropyrazole 1-oxide 

Relevant academic research and scientific papers

2-Substituted Pyrazole 1-Oxides. Preparation and Reaction with Electrophilic Reagents

1-Substituted pyrazoles have been oxidized by peracids to 2-substituted pyrazole 1-oxides.This leads to a change in reactivity towards electrophilic attack. 2-Benzylpyrazole 1-oxide is brominated, chlorinated, and nitrated selectively at C-3.The 3-halo-su

INTRODUCTION OF SUBSTITUENTS INTO 5-MEMBERED AZA-HETEROAROMATICS

With emphasis on mono- and regio-selectively, methods for introduction of substituents at nitrogen and carbon atoms of 5-membered aza-heteroaromatics have been developed.The methods involve application of activation and of assistant groups for direction and protection.Activation has been achieved by the use of quaternary azolium ions and azol-N-oxides as reactive intermediates.If necessary, the N-oxides were further activated by alkylation or acylation.