1451816-28-6Relevant articles and documents
Chemical synthesis of biologically active monoglycosylated GM2-activator protein analogue using N-sulfanylethylanilide peptide
Sato, Kohei,Shigenaga, Akira,Kitakaze, Keisuke,Sakamoto, Ken,Tsuji, Daisuke,Itoh, Kohji,Otaka, Akira
, p. 7855 - 7859 (2013)
Going to SEA(lide): Total chemical synthesis of a 162-residue glycoprotein analogue of the monoglycosylated human GM2-activator protein (GM2AP) was achieved. Key steps were the use of N-sulfanylethylanilide (SEAlide) peptides in the kinetic chemical ligation synthesis of a large peptide fragment, and a convergent native chemical ligation for final fragment assembly. Copyright
