145190-98-3 Usage
Uses
Used in Medical Diagnostics:
3-Tri-N-butylstannyl-phenylisothiocyanate is used as a reagent for the radioiodination of monoclonal antibodies. This process involves the attachment of radioactive iodine isotopes to antibodies, which can then be used for imaging and detecting specific cells or tissues in the body. The compound plays a crucial role in enhancing the efficiency and specificity of antibody labeling.
Used in Antibody Labelling:
In the field of antibody labeling, 3-Tri-N-butylstannyl-phenylisothiocyanate serves as a valuable agent for attaching radioactive markers to antibodies. This allows for the tracking and detection of target cells or tissues, which can be particularly useful in cancer diagnosis and treatment monitoring. The compound's properties enable it to facilitate the binding of radioactive isotopes to antibodies, improving the accuracy and effectiveness of diagnostic procedures.
Used in Pharmaceutical Research:
3-Tri-N-butylstannyl-phenylisothiocyanate may also be utilized in the development of new pharmaceuticals, particularly those targeting cancer cells. Its unique chemical properties make it a promising candidate for the design and synthesis of novel drug molecules, potentially leading to more effective treatments for various types of cancer.
Used in Chemical Synthesis:
In the chemical industry, 3-Tri-N-butylstannyl-phenylisothiocyanate can be employed as an intermediate or reagent in the synthesis of various organic compounds. Its organostannane nature allows for its use in specific chemical reactions, contributing to the development of new materials and products with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 145190-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,1,9 and 0 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 145190-98:
(8*1)+(7*4)+(6*5)+(5*1)+(4*9)+(3*0)+(2*9)+(1*8)=133
133 % 10 = 3
So 145190-98-3 is a valid CAS Registry Number.
145190-98-3Relevant academic research and scientific papers
Lee, Hyune-Jea,Torii, Daiki,Jeon, Yongju,Yoshida, Jun-Ichi,Kim, Heejin
, p. 1899 - 1902 (2020)
The isothiocyanate (NCS) group is an attractive functional group in the field of organic and pharmaceutical chemistry. It can be transformed into other heteroatomic functional groups. It usually acts as the inductive group of biological activity and has also been traditionally used as the fluorescent-labeling reagent. However, it is not compatible with strong bases. When the NCS group is at para position in halobenzenes, it generally undergoes nucleophilic additions upon reaction with strong bases. To the best of our knowledge, there is currently no general methodology for the formation and reactions of NCS-functionalized aryllithiums for meta and para substituents. Herein, we report the continuous-flow generation of NCS-substituted aryllithiums from the corresponding haloarenes via a selective halogen-lithium exchange reaction and its reaction with various electrophiles to yield NCS-containing products. We also achieved an integrated synthesis through sequential reactions of the NCS-containing compounds with additional nucleophiles using the continuous-flow reactors.
