1451983-98-4Relevant academic research and scientific papers
Rapid and efficient synthesis of [11C]ureas via the incorporation of [11C]CO2 into aliphatic and aromatic amines
Haji Dheere, Abdul Karim,Yusuf, Nadiya,Gee, Antony
, p. 8193 - 8195 (2013)
A rapid urea radiolabelling methodology has been developed. [ 11C]CO2 was activated by 1,8-diazabicycloundec-7-ene (DBU) in the presence of aliphatic and aromatic amines and reacted with Mitsunobu reagents to produce asymmetric 11C radiolabelled ureas in high radiochemical yields.
