1452036-49-5Relevant academic research and scientific papers
Enantioselective gold(I)-catalyzed vinylogous [3 + 2] cycloaddition between vinyldiazoacetates and enol ethers
Briones, John F.,Davies, Huw M. L.
supporting information, p. 13314 - 13317 (2013/09/24)
The reaction of vinyldiazoacetates with enol ethers catalyzed by the binuclear gold complex (R)-DTBMSegphos(AuCl)2 activated by silver hexafluoroantimonate results in a highly enantioselective [3 + 2] cycloaddition. The [3 + 2] cycloaddition proceeds with dynamic kinetic resolution when the enol ether is a 4-substituted 1-(methoxymethylene)cyclohexane. The reaction is initiated by nucleophilic attack of the vinyl ethers at the vinylogous position of the gold vinylcarbene intermediate.
