1452161-53-3

Upstream product

• 1452161-52-2 (6S,10S)-11-tert-butyldimethylsilyloxy-6,10-dibenzyloxy-4,8-dioxaundecene 
• 1452161-51-1 (2S,6S)-1-tert-butyldimethylsilyloxy-4,8-dioxaundeca-10-ene-2,6-diol 
• 1452161-50-0 (2S,6S)-1,2-O-isopropylidene-4,8-dioxaundeca-10-en-6-ol 
• 1452161-58-8 C₉H₁₈O₅ 

Downstream Products

• 1452161-57-7 5,10-dibenzyloxy-3,7,10-trioxacyclododecanone 

Relevant academic research and scientific papers

Short and stereocontrolled cyclic polyglycerols synthesis using BF 3·OEt2 mediated intramolecular epoxide-opening reaction

We developed a new method for the stereocontrolled synthesis of cyclic oligoglycerols. Optically pure solketal and epichlorohydrin were coupled with allyl alcohol under aqueous basic conditions to construct a linear triglycerol skeleton. After subsequent steps, the epoxy alcohol (7) obtained was treated with a catalytic amount of BF3·OEt2 in CH 2Cl2 to produce in a high yield of the desired cyclic triglycerol through a regioselective, intramolecular epoxide ring-opening reaction.