145241-75-4 Usage
General Description
6,8-Difluoroquinoline is a chemical compound with the molecular formula C9H5F2N. It is a quinoline derivative, which is a class of organic compounds that are often used in the pharmaceutical industry. 6,8-Difluoroquinoline is a fluorinated quinoline, meaning it contains two fluorine atoms in its structure. It is known for its various pharmacological properties, including its potential as an antimicrobial agent. This chemical compound has been studied for its potential application in the development of new drugs for the treatment of bacterial infections. Additionally, the presence of fluorine atoms in its structure can also potentially enhance its bioavailability and metabolic stability, making it a promising candidate for pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 145241-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,2,4 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 145241-75:
(8*1)+(7*4)+(6*5)+(5*2)+(4*4)+(3*1)+(2*7)+(1*5)=114
114 % 10 = 4
So 145241-75-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H5F2N/c10-7-4-6-2-1-3-12-9(6)8(11)5-7/h1-5H
145241-75-4Relevant articles and documents
Glycerol and Q-tubes: Green catalyst and technique for synthesis of polyfunctionally substituted heteroaromatics and anilines
AlMarzouq, Douaa Salman,Elnagdi, Noha M. Hilmy
, (2019/05/24)
The role of glycerol as a green bio-based solvent, reactant, and/or a catalyst in the synthesis of novel heterocycles, under pressure, is studied. Synthesis of novel quinolines in good yields using a new modified Skraup synthesis, utilizing glycerol and pressure Q-tubes, is demonstrated. Novel aniline trimers are prepared using glycerol, and substituted anilines under pressure, in acidic medium and water. Glycerol was employed as a catalyst and a green solvent in the synthesis of novel pyridazines 13a-c. The mechanisms of the reactions and the catalytic effect of glycerol in protic and aprotic media are fully discussed. The structures of the synthesized compounds were determined via X-ray crystallography and spectroscopic methods.
