145263-42-9Relevant academic research and scientific papers
An efficient asymmetric route to tertiary carbinols: Synthesis of (R)-mevalonolactone
Roy,Sharma,Dhotare,Vichare,Chattopadhyay,Chattopadhyay
, p. 1082 - 1090 (2008/02/02)
An efficient strategy for the asymmetric construction of tertiary carbinols has been devised using cyclohexylideneglyceraldehyde as a chiral template. This involves (a) addition of a Grignard reagent (R1MgX) to cyclohexylideneglyceraldehyde, fo
A synthesis of (R)-mevalonolactone
Ray, Nicholas C.,Raveendranath,Spencer, Thomas A.
, p. 9427 - 9432 (2007/10/02)
An enantioselective synthesis of (R)-mevalonolactone (1) has been accomplished starting from known epoxide 2, prepared with ?95% ee by asymmetric epoxidation of nerol. Functional group manipulation of 2 and ozonolysis afforded intermediate 8, which was co
