145264-80-8Relevant academic research and scientific papers
An efficient synthesis of 4-heterofunction-substituted 3-(1-hydroxy)ethylazetidin-2-ones from 3-(1-hydroxy)ethyl-4-phenylsulfinylazetidin-2-one by reaction with silylated heteronucleophiles
Kita,Shibata,Yoshida,Tohjo
, p. 1733 - 1736 (2007/10/02)
3-(1-tert-Butyldimethylsiloxy)ethyl-4-sulfinylazetidin-2-one was reacted with silylated N-, S-, O-, and P-nucleophiles in the presence of a catalytic amount of ZnI2 to give the corresponding trans-4-heterofunction-substituted azetidin-2-ones in high yields.
A NOVEL SUBSTITUTION REACTION OF 4-SULFINYLAZETIDIN-2-ONE WITH SILYLATED HETERONUCLEOPHILES: AN EFFICIENT SYNTHESIS OF 4-HETEROFUNCTION SUBSTITUTED 3-(1-HYDROXY)ETHYLAZETIDIN-2-ONES
Kita, Yasuyuki,Shibata, Norio,Yoshida, Naoki,Tohjo, Takashi
, p. 2375 - 2378 (2007/10/02)
4-Sulfinylazetidin-2-one was reacted with silylated heteronucleophiles in the presence of a catalytic amount of zinc iodide to give the corresponding trans-4-heterofunction substituted azetidin-2-ones in high yields.
