1452823-99-2

Upstream product

• 54555-84-9 benzyl iodoethyl ether 
• 30095-98-8 methyl (2-nitrophenyl)acetate 
• 1452823-72-1 potassium 4-(benzyloxy)2-(2-nitrophenyl)butanoate 
• 1452823-74-3 3-(3-((tert-butyldimethylsilyl)oxy)propyl)-3-ethylcyclopent-1-en-1-yl trifluoromethanesulfonate 
• 1452823-71-0 methyl 4-(benzyloxy)-2-(2-nitrophenyl)butanoate 

Relevant academic research and scientific papers

Palladium-catalyzed decarboxylative vinylation of potassium nitrophenyl acetate: Application to the total synthesis of (±)-goniomitine

Merge and divert: The natural product (±)-goniomitine was synthesized by a method featuring two key steps: 1) fragment coupling to a functionalized cyclopentene by a novel palladium-catalyzed decarboxylative vinylation reaction and 2) an unprecedented one-pot integrated oxidation/reduction/cyclization (IORC) process to convert the substituted cyclopentene into the tetracyclic skeleton of goniomitine with high chemo-, regio-, and diastereoselectivity.