1452830-89-5Relevant academic research and scientific papers
A strategy to access fused triazoloquinoline and related nucleoside analogues
Upadhyaya, Kapil,Ajay, Arya,Mahar, Rohit,Pandey, Renu,Kumar, Brijesh,Shukla, Sanjeev K.,Tripathi, Rama Pati
, p. 8547 - 8558 (2013/09/12)
Fused triazoloquinolines have been prepared starting from (E)-3-(2-nitrophenyl)-1-aryl-prop-2-en-1-ones and sugar or benzyl azides in a sequential [3+2] cycloaddition reaction, followed by one pot Pd-C assisted reduction, cyclization and aromatization. The triazolyl fused quinolines with N1-glycosyl substituents as unnatural nucleosides have inherent potential to generate a library of compounds for bioevaluations.
