1453083-81-2Relevant academic research and scientific papers
Homologation as a lead modification approach en route to a series of lactone-based muscarinic ligands
Gao, Rong,Bhandare, Richie R.,Canney, Daniel J.
, p. 1023 - 1030 (2014/03/21)
Previous work identified the lactone ring as a useful scaffold for the design of muscarinic ligands and reported a lactone-based ligand with an IC 50 of 340 nM. Using homologation as a lead modification approach, a new series of lactone-based c
