1453083-93-6

Upstream product

• 1660-94-2 Tetraethyl methylenediphosphonate 
• 2417-72-3 Methyl 4-(bromomethyl)benzoate 

Downstream Products

• 1207631-33-1 tetraethyl 2-(4-carboxyphenyl)ethane-1,1-bis(phosphonate) 
• 1453083-94-7 2-(4-carboxyphenyl)ethane-1,1-bis(phosphonic acid) 
• 1453083-98-1 C₃₆H₄₁N₃O₈P₂ 

Relevant academic research and scientific papers

BONE TARGETED ANTIMICROBIAL OXAZOLIDINONE RELATED COMPOUNDS, FORMULATIONS THEREOF, AND USES THEREOF

Described herein are bisphosphonate oxazolidinone compounds, and conjugates and pharmaceutical formulations thereof, that can include a bisphosphonate and an oxazolidinone (or an oxazolidinone antimicrobial or antibiotic agent, substituent or derivative thereof), where the oxazolidinone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate oxazolidinone compounds, conjugates and pharmaceutical formulations thereof. Also provided herein are methods of use of the compounds, conjugates and formulations for treating a bone disease or for use in preparing a formulation for the treatment a bone disease.

Bis(phosphonate)-building blocks modified with fluorescent dyes

Preparation of two benzylic bis(phosphonic acids) modified with primary amine or carboxylic acid groups on the benzene ring is described. These compounds were prepared and characterized in the form of both bis(phosphonate) tetraesters and corresponding fr