1453084-85-9Relevant academic research and scientific papers
Mycalol: A natural lipid with promising cytotoxic properties against human anaplastic thyroid carcinoma cells
Cutignano, Adele,Nuzzo, Genoveffa,D'Angelo, Daniela,Borbone, Eleonora,Fusco, Alfredo,Fontana, Angelo
, p. 9256 - 9260 (2013)
From Antarctic waters: Human anaplastic thyroid carcinoma (ATC) cells which stably express antisense construct against nuclear high-mobility groupA (HMGA) proteins were used in a novel phenotypic assay for screening marine natural extracts. The rational search led to the isolation and identification of a novel polyoxygenated linear lipid (1) that showed important and selective cytotoxicity against ATC-derived tumor cell lines. Copyright
